1. Is the over-the-counter (OTC) at-home test just as good?
While the OTC tests that are dropped into the toilet are fairly
sensitive, your doctor may prefer the gFOBT or one of the immunochemical FOBTs. Since the color change that is observed is subject to the interpretation of the observer, the tests sent to a professional laboratory may be more reliable. The staff are more experienced than most patients in interpreting the sometimes subtle color change and are more familiar with sources of
false negative and
false positive results.
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2. What kind of procedures might follow a positive FOBT?
An FOBT may be preceded or followed by a
digital rectal exam. A positive FOBT may be followed by:
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3. Are there any other types of tests for colorectal cancer that are run on stool samples?
Yes. There is a stool DNA (sDNA) test available. The test can detect certain alterations to DNA in cancer cells shed into the stool. Studies have shown that the test has acceptable
sensitivity, although it cannot identify all types of
colorectal cancer. Guidelines released in March 2008 jointly by the American Cancer Society, the American College of Radiology, and the US Multi-Society Task Force on Colorectal Cancer added sDNA to their list of recommended testing options for colorectal cancer screening.
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