Lipase

With acute pancreatitis there is usually no long term damage, and often no further problems develop. Chronic pancreatitis, which may present as a series of acute attacks or as an ongoing upset can cause permanent damage. As the pancreas becomes more scarred, some people develop diabetes and/or the inability to digest foods, especially fats. The lack of normal pancreatic enzymes may lead to adverse effects on food digestion and waste production, causing abdominal pain, greasy stools, and formation of stones in the pancreas. Even if the disease is controlled, the damage done is often irreversible. If the disease progresses, it could lead to death.

In some cases, an elevated lipase may be due to a condition other than pancreatitis. In pancreatitis, the lipase rises quickly quickly and drops in 5 to 7 days. In other conditions, the rise is usually not as great, and the level may be maintained for a longer period. Your doctor is the best one to determine if you have a pancreatic disorder. He will make a diagnosis based on your symptoms, medical history, and test results.

Blood amylase levels are sensitive for pancreatic disorders but are not specific. An elevated amylase may indicate a problem but nonpancreatic disorders can cause increased amylase levels. Lipase levels are usually increased in pancreatic disorders and are more specific than amylase for diseases of the pancreas. Evaluating the results of the two tests together help to diagnose or rule out pancreatitis and other conditions.