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Breast Cancer
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Treatment
Most breast cancers are treated by surgically removing the cancer, or as much of the cancer as possible, and then using one or more other therapies to kill or control any remaining cancerous cells. A lumpectomy removes the cancerous tissue while leaving the remaining breast tissue intact. A mastectomy is a more far-reaching surgical procedure but can vary in the amount of breast and surrounding tissue removed. While mastectomy was once the preferred treatment even in early stage breast cancer, more choices have become available. Lumpectomy followed by radiation has been demonstrated to be as effective as a mastectomy in treating many early stage breast cancers. In performing either a lumpectomy or mastectomy, a doctor may remove some or all of the lymph nodes under the arm and submit them for pathological examination to determine if the cancer has spread.
The use of radiation, chemotherapy, and other drug therapies depends on the woman, on the cancer’s characteristics, and on how far the cancer has spread. Drug therapies may include tamoxifen, aromatase inhibitors, and other anti-estrogen drugs that target hormone-sensitive cancers. Those who over-express the Her-2/neu protein may benefit from Herceptin (Trastuzumab) therapy. There is a great deal of new research being performed in the field of breast cancer treatment, and your doctor is your best source of information. New drugs with fewer side effects than existing therapies are being developed. There are also promising gene-targeting drugs and vaccines, some of which are already being used on a limited, or trial, basis.
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Related Pages
 On This Site
Tests: BRCA-1 and BRCA-2, Tumor markers, CA 15-3, Her-2/neu, Hormone receptor status, Multiparameter Gene Expression Tests for Breast Cancer
Screening: Young Adults (19-29), Adults (30-49), Adults (50 and up)
In the News: Gene Expression Test for Breast Cancer Now Included in Guidelines (2008), Test Reflects Progress in Personalizing Breast Cancer Treatment (2006), BRCA Genetic Test Misses Some Mutations (2006), Breast Cancer Test Predicts Chances of Recurrence (2005), New Test May Help Predict Patients' Chances of Surviving Metastatic Breast Cancer (2005), Task Force Favors BRCA Screening for Women at High Risk (2005)
 Elsewhere On The Web
This article last reviewed on March 24, 2008
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